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Description
Nectin-4 Recombinant Rabbit mAb (SDT-277-229)Product Specification Host Rabbit Antigen NECTIN 4 Synonyms LNIR, PRR4, PVRL4 Immunogen Recombinant Protein Location Cell membrane Accession Q96NY8 Clone Number SDT 277 229 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Tag N A Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution,
Product Specification
| Host | Rabbit |
| Antigen | NECTIN-4 |
| Synonyms | LNIR, PRR4, PVRL4 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | Q96NY8 |
| Clone Number | SDT-277-229 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Tag | N/A |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 |
Background
The Nectin cell adhesion molecule (Nectin) family members are Ca2+‑independent immunoglobulin‑like cellular adhesion molecules (including Nectins 1‑4), involved in cell adhesion via homophilic/heterophilic interplay. In addition, the Nectin family plays a significant role in enhancing cellular viability and movement ability. In contrast to enrichment of Nectins 1‑3 in normal tissues, Nectin‑4 is particularly overexpressed in a number of tumor types, including breast, lung, urothelial, colorectal, pancreatic and ovarian cancer. Moreover, the upregulation of Nectin‑4 is an independent biomarker for overall survival in numerous cancer types [PMID: 34664682].
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