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Description
Human IgG F(c) Recombinant Rabbit mAb (SDT-318-21)Product Specification Host Rabbit Antigen Human IgG Synonyms Immunoglobulin heavy constant gamma Immunogen Native protein Location Secreted, Cell membrane Accession P01859 P01860 P01861P01857 Clone Number SDT 318 21 Antibody Type Recombinant mAb Application ELISA, WB, IHC P Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | Human IgG |
| Synonyms | Immunoglobulin heavy constant gamma |
| Immunogen | Native protein |
| Location | Secreted, Cell membrane |
| Accession | P01859、 P01860、 P01861、P01857 |
| Clone Number | SDT-318-21 |
| Antibody Type | Recombinant mAb |
| Application | ELISA, WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:20000 | null |
| IHC-P | 1:2000 | null |
Background
The intact antibody of human immunoglobulin (IgG) is composed of the fragment for antigen binding (Fab) and the crystallizable fragment (Fc) for binding of Fcγ receptors. Among the four subclasses of human IgG (IgG1, IgG2, IgG3, IgG4), which differ in their constant regions, particularly in their hinges and CH2 domains, IgG1 has the highest FcγR-binding affinity, followed by IgG3, IgG2, and IgG4 [PMID: 32370812].
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Exchange/Return Notes
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