SKU: 92117622711

LIGANDROL (LGD-4033) Solution, 300mg (10mg/mL)

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Description

LIGANDROL (LGD-4033) Solution, 300mg (10mg/mL)LIGANDROL (LGD 4033) LGD 4033, also known as Ligandrol, VK5211, or Anabolicum, is a Selective Androgen Receptor Modulator (SARM). Various animal studies have demonstrated that it increases anabolic activity in muscles. It has also shown positive effects on bone density in male rats suffering from hypogonadism and has been successful in treating female postmenopausal rats experiencing osteoporosis. LGD 4033: Effects on Bones and Muscles Research

LIGANDROL (LGD-4033)

LGD 4033, also known as Ligandrol, VK5211, or Anabolicum, is a Selective Androgen Receptor Modulator (SARM). Various animal studies have demonstrated that it increases anabolic activity in muscles. It has also shown positive effects on bone density in male rats suffering from hypogonadism and has been successful in treating female postmenopausal rats experiencing osteoporosis.

LGD 4033: Effects on Bones and Muscles

Research presented at the 62nd Annual Meeting of the Gerontology Society of America revealed that the use of LGD 4033 in animals increased both resistance to fractures and bone mineral density after 12 weeks. These effects were observed in porous bone at a dose of 0.3 mg/kg per day and in cortical bone at a dose of 0.03 mg/kg per day (source).

In both hypogonadal and normal rats, LGD 4033 increased skeletal muscle mass and the diameter of muscle fibers. This correlated with an increased contractile strength of the muscles, indicating improved muscle power.

In an intriguing study conducted by Roche et al., 3-month-old Sprague-Dawley rats underwent ovariectomy and were treated with LGD 4033 for 5 weeks. Rats in the experimental groups received doses ranging from 0.04 to 4 mg/kg of body weight per day. Subsequent analyses were performed on fiber size, capillary density, and various enzyme levels. Additionally, the weights of the uterus, gastrocnemius, and soleus muscles were measured before and after treatment (source).

In analyzing the effects of LGD 4033, researchers also took samples from the quadriceps femoris muscle to measure changes in intramuscular fat content. Treatment with LGD 4033 resulted in an increased capillary density and higher enzymatic activity of both citrate synthase in the gastrocnemius muscle and lactate dehydrogenase in the longissimus muscle (source).

Concentration
10mg/ml.

Half Life
24 – 36 hours.

DISCLAIMER
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or domestic use. Please familiarize yourself with our DISCLAIMER before ordering.

Data Sheet

LIGANDROL (LGD-4033) Solution, 300mg (10mg/mL)

Application Selective Androgen Receptor Modulator
CAS 1165910-22-4
Molar Mass 338.25 g/mol
Chemical Formula C14H12F6N2O
IUPAC Name 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Synonyms LG4, LG-4, 1165910-22-4, UNII-1EJT54415A, 4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile, 1EJT54415A, 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrile, 4-{(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]-1-pyrrolidinyl}-2-(trifluoromethyl)benzonitrile, SCHEMBL221159, DTXSID10657620, EX-A729, PUBCHEM_44137686, BCP07128, s8822, ZINC95830588, AKOS022173564, CS-4667, DB13934, AC-30218, AK141891, HY-13981, AX8259791, A14346, J-690039, Q21098841, 4-[(2R)-2-[(1R)-2,2,2-TRIFLUORO-1-HYDROXYETHYL]PYRROLIDIN-1-YL]-2-(TRIFLUOROMETHYL)BENZONITRILE, Benzonitrile, 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)-
Storage Room temperature
Solubility Soluble in Ethanol, PEG400, PG, Glycerin
Organoleptic Profile Slightly Occluded Clear Liquid
Physical Form Solution in PEG400
Specification 10mg/mL ±5%
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.
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SKU: 92117622711

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Chae
Pawtucket, US
★★★★★ 5
Great quality for the price!
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This body shimmer oil gives a really nice sun-kissed glow without looking overly glittery. The shimmer is subtle and smooth, so it catches the light in a flattering way instead of looking chunky or artificial. It works especially well on areas like the shoulders, collarbones, and legs for that summer glow effect. The texture is lightweight and absorbs nicely into the skin. It doesn’t feel greasy, and it leaves the skin feeling soft and moisturized after applying. The bronze shade adds a warm tone that enhances natural skin color while still looking natural. It’s also pretty versatile. You can use it on its own for a glowing finish or mix a small amount with foundation, lotion, or sunscreen to add a bit of radiance. It blends easily and spreads evenly, so a little goes a long way. The result is smooth, hydrated skin with a subtle luminous shine that looks great in sunlight.
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Reviewed in the United States on March 15, 2026
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Customer Review
San Leandro, US
★★★★★ 4
Glowy but not sure about the spf
Color: Glistening Bronze
My first impression was that this works more like a basic body shimmer than anything else. The Glistening Bronze shade gives a noticeable glow, especially on arms and shoulders. It spreads easily and adds a warm shimmer in the light, but the overall effect feels pretty simple and more cosmetic than skincare focused. In use, the oil blends in smoothly and feels lightweight on the skin. It does leave a bit of moisture behind, similar to a light body oil, and the shimmer shows up well outdoors. The bronze tone is fairly deep, so it seems better suited for medium to darker skin tones or anyone who wants a stronger bronzed glow. The product mentions SPF 45, but there is very little information about the sun protection side of it, so I personally treat this more like a shimmer oil than a sunscreen. Overall, this is fine if you are mainly looking for a body shimmer that adds glow and a bronzed look. It does the job of giving skin a subtle shine and a bit of hydration, but it does not stand out as anything particularly special. I would recommend it mostly for people who want a simple shimmering body oil rather than relying on it for sun protection.
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Reviewed in the United States on March 15, 2026
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Be Beautiful
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★★★★★ 5
Glamorize your sunny day outing with this shimmer suntan protection
Color: Glistening Bronze, Color: Glistening Bronze
This body shimmer oil has a natural glow luminizer in it. It has an SPF of 45 for sun protection factor. This went on smoothly and easily and was light and did not feel greasy. It felt like fancy suntan lotion like no other I've ever tried before. This just adds a little glamor to your sunny day outing
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Reviewed in the United States on March 20, 2026
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Aimee inman
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★★★★★ 5
Glowy, Lightweight Summer Shine
Color: Glistening Bronze, Color: Glistening Bronze
This gives a really pretty sun-kissed glow without feeling greasy or heavy on the skin. The shimmer is noticeable but not over-the-top, and it blends nicely for a smooth, radiant finish. I also like that it has SPF, which makes it perfect for everyday summer use.
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Olive Oil
Charlottesville, US
★★★★★ 3
This Oil Definitely Glitters!
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I really wanted to love this shimmer oil, but it's unfortunately not my favorite. I love that it has SPF! That is a big win for me! The oil is also very good at hydrating my skin, which I appreciate. My problem comes with the shimmer of the product. The glitter in it is too big for my liking. With it being called a shimmer oil, I expected tiny glitter that softly shimmers like shimmer powders, lotions, and oils usually do. But this stuff glit-ters! And because it's bigger sized glitter, it's a lot easier to see when it gets all over everything like clothes, furniture, spouses and children. If the shimmering glitter in this was just smaller and softer, I would love this for summer time to use on my legs and arms. But it's unfortunately just not my favorite and I don't think I'll be using it anymore.
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Reviewed in the United States on May 10, 2026

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