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Description
CD163 Recombinant Rabbit mAb (SDT-327-58)Product Specification Host Rabbit Antigen CD163 Synonyms M130 Immunogen Recombinant Protein Location Secreted, Cell membrane Accession Q2VLH6 Clone Number SDT 327 58 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 25 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20 C as
Product Specification
| Host | Rabbit |
| Antigen | CD163 |
| Synonyms | M130 |
| Immunogen | Recombinant Protein |
| Location | Secreted, Cell membrane |
| Accession | Q2VLH6 |
| Clone Number | SDT-327-58 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | null |
| IHC-P | 1:1000 | null |
Background
CD163 is a monocyte/macrophage specific marker expressed predominantly on cells which possess strong anti-inflammatory potential. The expression of CD163 is strongly induced by anti-inflammatory mediators such as glucocorticoids and interleukin-10, while being inhibited by pro-inflammatory mediators such as interferon-gamma. CD163-expressing mononuclear phagocytes, as well as soluble CD163, may both take part in downregulating an inflammatory response [PubMed: 22038213].
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